1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. MALT1


MALT1 is a paracaspase, which is related to the caspase (cysteine-aspartic proteases) family of proteases but cleaves after Arg residues instead of Asp. MALT1 cleavage activity is linked to the pathogenesis of activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL), a chemoresistant form of DLBCL. MALT1 is a unique paracaspase protein that transduces aberrant oncogenic signaling in ABC-DLBCL. MALT1 represents a potentially important therapeutic target for ABC-DLBCL and MALT lymphoma. MALT1 small molecule inhibitors might be useful chemical tools for studying MALT1 biology and treating MALT1-addicted tumors.

MALT1 相关产品 (3):

Cat. No. Product Name Effect Purity
  • HY-12276
    MALT1 inhibitor MI-2 Inhibitor 99.56%
    MALT1 inhibitor MI-2 是一种不可逆的 MALT1 蛋白酶抑制剂,IC50 为 5.84 μM。
  • HY-115466
    MLT-748 Inhibitor
    MLT-748 是一种有效、选择性的 MALT1 的别构抑制剂,与 MALT1 的别构 Trp580 口袋结合,IC50 值为 5 nM。
  • HY-124587
    MLT-747 Inhibitor
    MLT-747 是一种有效、选择性的 MALT1 的别构抑制剂,与 MALT1 的别构 Trp580 口袋结合,IC50 值为 14 nM。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

开门彩平台 网易彩票 五百万彩票 36彩票平台 运盛彩票平台 亿人彩票平台 亿菲彩票平台 大福彩票 小财神彩票平台 易旺彩票平台