AMG 333 

目录号: HY-112703
产品使用指南

AMG 333是有效,高选择性的 TRPM8 拮抗剂,IC50为13 nM。

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AMG 333 Chemical Structure

AMG 333 Chemical Structure

CAS No. : 1416799-28-4

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Description

AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.

IC50 & Target

IC50: 13 nM (TRPM8)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2059 mL 11.0297 mL 22.0595 mL
5 mM 0.4412 mL 2.2059 mL 4.4119 mL
10 mM 0.2206 mL 1.1030 mL 2.2059 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • [1].

Molecular Weight

453.32

Formula

C₂₀H₁₂F₅N₃O₄

CAS No.

1416799-28-4

SMILES

FC1=CC=CN=C1[C@H](C2=CC(F)=C(OC(F)(F)F)C=C2)NC(C3=NC=C(C(O)=O)C=C3)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • [1]。

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
AMG 333
目录号:
HY-112703
需求量:

AMG 333

Cat. No.: HY-112703

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